L-isoleucine, along with L-valine, and L-leucine, is one of the branched-chain amino acids (BCAAs). It is strongly hydrophobic and features two chiral carbon atoms in its structure. Of the four possible stereoisomers, only one occurs naturally in proteins. Physiologically, it serves as a nitrogen donor and plays a role in glucose utilization, fatty acid metabolism, and the regulation of immune function.
It is important to note that L-isoleucine is an essential amino acid, which means the human body cannot synthesize it and it must be acquired through dietary sources. On average, adults need about 0.7 grams per day.
The incorporation of L-valine in cosmetics can enhance their moisturizing properties and support collagen synthesis. It is one of the amino acids that contribute to the skin’s natural moisturizing factor (NMF), which plays a key role in maintaining adequate hydration and safeguarding the skin’s outer layer.
